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Timing Constraints of In Vivo Gag Mutations during Primary HIV-1 Subtype C Infection

BACKGROUND: Aiming to answer the broad question “When does mutation occur?” this study examined the time of appearance, dominance, and completeness of in vivo Gag mutations in primary HIV-1 subtype C infection. METHODS: A primary HIV-1C infection cohort comprised of 8 acutely and 34 recently infecte...

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Detalles Bibliográficos
Autores principales: Novitsky, Vladimir, Wang, Rui, Margolin, Lauren, Baca, Jeannie, Kebaabetswe, Lemme, Rossenkhan, Raabya, Bonney, Caitlin, Herzig, Michaela, Nkwe, David, Moyo, Sikhulile, Musonda, Rosemary, Woldegabriel, Elias, van Widenfelt, Erik, Makhema, Joseph, Lagakos, Stephen, Essex, M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768328/
https://www.ncbi.nlm.nih.gov/pubmed/19890401
http://dx.doi.org/10.1371/journal.pone.0007727