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Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis

BACKGROUND: Enhancer of zeste homologue 2 (EZH2) is a member of the Polycomb group of genes that is involved in epigenetic silencing and cell cycle regulation. METHODS: We studied EZH2 expression in 409 patients with colorectal cancer stages II and III. The patients were included in a randomised stu...

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Detalles Bibliográficos
Autores principales: Fluge, Ø, Gravdal, K, Carlsen, E, Vonen, B, Kjellevold, K, Refsum, S, Lilleng, R, Eide, T J, Halvorsen, T B, Tveit, K M, Otte, A P, Akslen, L A, Dahl, O
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768450/
https://www.ncbi.nlm.nih.gov/pubmed/19773751
http://dx.doi.org/10.1038/sj.bjc.6605333