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DKC1 overexpression associated with prostate cancer progression

BACKGROUND: Dyskerin encoded by the DKC1 gene is a predominantly nucleolar protein essential for the formation of pseudouridine in RNA and the telomerase RNA subunit hTR. Inherited mutations inactivating dyskerin cause dyskeratosis congenita, a syndrome with progeroid features characterised by skin...

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Detalles Bibliográficos
Autores principales: Sieron, P, Hader, C, Hatina, J, Engers, R, Wlazlinski, A, Müller, M, Schulz, W A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768451/
https://www.ncbi.nlm.nih.gov/pubmed/19755982
http://dx.doi.org/10.1038/sj.bjc.6605299