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Tetraspanin-induced death of myeloma cell lines is autophagic and involves increased UPR signalling
BACKGROUND: Multiple myeloma (MM) therapy is hindered by the interaction of the heterogeneous malignant plasma cells with their microenvironment and evolving drug resistance. We have previously shown that the membranal tetraspanins, CD81 and CD82, are under-expressed in MM cells and that their reint...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768457/ https://www.ncbi.nlm.nih.gov/pubmed/19755988 http://dx.doi.org/10.1038/sj.bjc.6605291 |