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Tetraspanin-induced death of myeloma cell lines is autophagic and involves increased UPR signalling

BACKGROUND: Multiple myeloma (MM) therapy is hindered by the interaction of the heterogeneous malignant plasma cells with their microenvironment and evolving drug resistance. We have previously shown that the membranal tetraspanins, CD81 and CD82, are under-expressed in MM cells and that their reint...

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Detalles Bibliográficos
Autores principales: Zismanov, V, Lishner, M, Tartakover-Matalon, S, Radnay, J, Shapiro, H, Drucker, L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768457/
https://www.ncbi.nlm.nih.gov/pubmed/19755988
http://dx.doi.org/10.1038/sj.bjc.6605291