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Open-label, clinical phase I studies of tasquinimod in patients with castration-resistant prostate cancer
BACKGROUND: Tasquinimod is a quinoline-3-carboxamide derivative with anti-angiogenic activity. Two open-label phase I clinical trials in patients were conducted to evaluate the safety and tolerability of tasquinimod, with additional pharmacokinetic and efficacy assessments. METHODS: Patients with ca...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768463/ https://www.ncbi.nlm.nih.gov/pubmed/19755981 http://dx.doi.org/10.1038/sj.bjc.6605322 |