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Danger signal and PAMP sensing define binary signaling pathways upstream of Toll

In drosophila, fungal and Gram-positive bacterial molecular determinants are detected by circulating pattern recognition receptors (PRRs). Previous findings suggest that these PRRs activate yet unidentified serine protease cascades culminating in the cleavage of Spaetzle, the endogenous Toll recepto...

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Detalles Bibliográficos
Autores principales: Chamy, Laure El, Leclerc, Vincent, Caldelari, Isabelle, Reichhart, Jean-Marc
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768518/
https://www.ncbi.nlm.nih.gov/pubmed/18724373
http://dx.doi.org/10.1038/ni.1643