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Danger signal and PAMP sensing define binary signaling pathways upstream of Toll
In drosophila, fungal and Gram-positive bacterial molecular determinants are detected by circulating pattern recognition receptors (PRRs). Previous findings suggest that these PRRs activate yet unidentified serine protease cascades culminating in the cleavage of Spaetzle, the endogenous Toll recepto...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768518/ https://www.ncbi.nlm.nih.gov/pubmed/18724373 http://dx.doi.org/10.1038/ni.1643 |