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Ethyl pyruvate reduces mortality in an endotoxin-induced severe acute lung injury mouse model

BACKGROUND: Ethyl pyruvate (EP) was recently identified as an experimental therapeutic agent in a wide variety of model systems for inflammation-mediated tissue and cellular injury. OBJECTIVE: To evaluate the effect of ethyl EP on improving the survival in mice with LPS-induced acute lung injury (AL...

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Detalles Bibliográficos
Autores principales: Shang, Guan-Hong, Lin, Dian-Jie, Xiao, Wei, Jia, Chong-Qi, Li, Yu, Wang, Ai-Hua, Dong, Liang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768703/
https://www.ncbi.nlm.nih.gov/pubmed/19799777
http://dx.doi.org/10.1186/1465-9921-10-91