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Clinical effectiveness and cost-effectiveness of pegvisomant for the treatment of acromegaly: a systematic review and economic evaluation

BACKGROUND: Acromegaly, an orphan disease usually caused by a benign pituitary tumour, is characterised by hyper-secretion of growth hormone (GH) and insulin-like growth factor I (IGF-1). It is associated with reduced life expectancy, cardiovascular problems, a variety of insidiously progressing det...

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Detalles Bibliográficos
Autores principales: Moore, David J, Adi, Yaser, Connock, Martin J, Bayliss, Sue
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768727/
https://www.ncbi.nlm.nih.gov/pubmed/19814797
http://dx.doi.org/10.1186/1472-6823-9-20