Cannabinoid receptor 2 mediates retention of immature B cells in bone marrow sinusoids

Immature B-cells developing in the bone marrow (BM) are found in parenchyma and sinusoids. The mechanisms controlling B-cell positioning within sinusoids are not understood. Here we showed that integrin α(4)β(1) and VCAM-1 are required, whereas CXCR4 is dispensable for sinusoidal retention. Instead,...

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Detalles Bibliográficos
Autores principales: Pereira, João P., An, Jinping, Xu, Ying, Huang, Yong, Cyster, Jason G.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768754/
https://www.ncbi.nlm.nih.gov/pubmed/19252491
http://dx.doi.org/10.1038/ni.1710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768754/
https://www.ncbi.nlm.nih.gov/pubmed/19252491
http://dx.doi.org/10.1038/ni.1710

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