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Cannabinoid receptor 2 mediates retention of immature B cells in bone marrow sinusoids
Immature B-cells developing in the bone marrow (BM) are found in parenchyma and sinusoids. The mechanisms controlling B-cell positioning within sinusoids are not understood. Here we showed that integrin α(4)β(1) and VCAM-1 are required, whereas CXCR4 is dispensable for sinusoidal retention. Instead,...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768754/ https://www.ncbi.nlm.nih.gov/pubmed/19252491 http://dx.doi.org/10.1038/ni.1710 |