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Orientation of palmitoylated Ca(V)β2a relative to Ca(V)2.2 is critical for slow pathway modulation of N-type Ca(2+) current by tachykinin receptor activation
The G(q)-coupled tachykinin receptor (neurokinin-1 receptor [NK-1R]) modulates N-type Ca(2+) channel (Ca(V)2.2 or N channel) activity at two distinct sites by a pathway involving a lipid metabolite, most likely arachidonic acid (AA). In another study published in this issue (Heneghan et al. 2009. J....
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768804/ https://www.ncbi.nlm.nih.gov/pubmed/19858358 http://dx.doi.org/10.1085/jgp.200910204 |