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Orientation of palmitoylated Ca(V)β2a relative to Ca(V)2.2 is critical for slow pathway modulation of N-type Ca(2+) current by tachykinin receptor activation

The G(q)-coupled tachykinin receptor (neurokinin-1 receptor [NK-1R]) modulates N-type Ca(2+) channel (Ca(V)2.2 or N channel) activity at two distinct sites by a pathway involving a lipid metabolite, most likely arachidonic acid (AA). In another study published in this issue (Heneghan et al. 2009. J....

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Detalles Bibliográficos
Autores principales:	Mitra-Ganguli, Tora, Vitko, Iuliia, Perez-Reyes, Edward, Rittenhouse, Ann R.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768804/ https://www.ncbi.nlm.nih.gov/pubmed/19858358 http://dx.doi.org/10.1085/jgp.200910204

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