Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD

Unwanted proteins in the endoplasmic reticulum (ER) are exported into the cytoplasm and degraded by the proteasome through the ER-associated protein degradation pathway (ERAD). Disturbances in ERAD are linked to ER stress, which has been implicated in the pathogenesis of several human diseases. Howe...

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Detalles Bibliográficos
Autores principales: Lim, Precious J., Danner, Rebecca, Liang, Jing, Doong, Howard, Harman, Christine, Srinivasan, Deepa, Rothenberg, Cara, Wang, Hongmin, Ye, Yihong, Fang, Shengyun, Monteiro, Mervyn J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768832/
https://www.ncbi.nlm.nih.gov/pubmed/19822669
http://dx.doi.org/10.1083/jcb.200903024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768832/
https://www.ncbi.nlm.nih.gov/pubmed/19822669
http://dx.doi.org/10.1083/jcb.200903024

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