PIKfyve regulates Ca(V)1.2 degradation and prevents excitotoxic cell death

Voltage-gated Ca(2+) channels (VGCCs) play a key role in neuronal signaling but can also contribute to cellular dysfunction and death under pathological conditions such as stroke and neurodegenerative diseases. We report that activation of N-methyl-d-aspartic acid receptors causes internalization an...

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Detalles Bibliográficos
Autores principales: Tsuruta, Fuminori, Green, Eric M., Rousset, Matthieu, Dolmetsch, Ricardo E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768838/
https://www.ncbi.nlm.nih.gov/pubmed/19841139
http://dx.doi.org/10.1083/jcb.200903028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768838/
https://www.ncbi.nlm.nih.gov/pubmed/19841139
http://dx.doi.org/10.1083/jcb.200903028

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