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PIKfyve regulates Ca(V)1.2 degradation and prevents excitotoxic cell death
Voltage-gated Ca(2+) channels (VGCCs) play a key role in neuronal signaling but can also contribute to cellular dysfunction and death under pathological conditions such as stroke and neurodegenerative diseases. We report that activation of N-methyl-d-aspartic acid receptors causes internalization an...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768838/ https://www.ncbi.nlm.nih.gov/pubmed/19841139 http://dx.doi.org/10.1083/jcb.200903028 |