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AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis

Specialized cell types exploit endosomal trafficking to deliver protein cargoes to cell type–specific lysosome-related organelles (LROs), but how endosomes are specified for this function is not known. In this study, we show that the clathrin adaptor AP-1 and the kinesin motor KIF13A together create...

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Detalles Bibliográficos
Autores principales: Delevoye, Cédric, Hurbain, Ilse, Tenza, Danièle, Sibarita, Jean-Baptiste, Uzan-Gafsou, Stéphanie, Ohno, Hiroshi, Geerts, Willie J.C., Verkleij, Arie J., Salamero, Jean, Marks, Michael S., Raposo, Graça
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768840/
https://www.ncbi.nlm.nih.gov/pubmed/19841138
http://dx.doi.org/10.1083/jcb.200907122