Leukotriene E(4)–induced pulmonary inflammation is mediated by the P2Y(12) receptor

Of the potent lipid inflammatory mediators comprising the cysteinyl leukotrienes (LTs; LTC(4), LTD(4), and LTE(4)), only LTE(4) is stable and abundant in vivo. Although LTE(4) shows negligible activity at the type 1 and 2 receptors for cys-LTs (CysLT(1)R and CysLT(2)R), it is a powerful inducer of m...

Descripción completa

Detalles Bibliográficos
Autores principales: Paruchuri, Sailaja, Tashimo, Hiroyuki, Feng, Chunli, Maekawa, Akiko, Xing, Wei, Jiang, Yongfeng, Kanaoka, Yoshihide, Conley, Pamela, Boyce, Joshua A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768854/
https://www.ncbi.nlm.nih.gov/pubmed/19822647
http://dx.doi.org/10.1084/jem.20091240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768854/
https://www.ncbi.nlm.nih.gov/pubmed/19822647
http://dx.doi.org/10.1084/jem.20091240

Ejemplares similares