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Transforming growth factor β is dispensable for the molecular orchestration of Th17 cell differentiation

Interleukin (IL)-17–producing T helper (Th17) cells play a critical role in the pathophysiology of several autoimmune disorders. The differentiation of Th17 cells requires the simultaneous presence of an unusual combination of cytokines: IL-6, a proinflammatory cytokine, and transforming growth fact...

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Detalles Bibliográficos
Autores principales: Das, Jyoti, Ren, Guangwen, Zhang, Liying, Roberts, Arthur I., Zhao, Xin, Bothwell, Alfred L.M., Van Kaer, Luc, Shi, Yufang, Das, Gobardhan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768861/
https://www.ncbi.nlm.nih.gov/pubmed/19808254
http://dx.doi.org/10.1084/jem.20082286