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Runx proteins regulate Foxp3 expression

Runx proteins are essential for hematopoiesis and play an important role in T cell development by regulating key target genes, such as CD4 and CD8 as well as lymphokine genes, during the specialization of naive CD4 T cells into distinct T helper subsets. In regulatory T (T reg) cells, the signature...

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Detalles Bibliográficos
Autores principales: Bruno, Ludovica, Mazzarella, Luca, Hoogenkamp, Maarten, Hertweck, Arnulf, Cobb, Bradley S., Sauer, Stephan, Hadjur, Suzana, Leleu, Marion, Naoe, Yoshinori, Telfer, Janice C., Bonifer, Constanze, Taniuchi, Ichiro, Fisher, Amanda G., Merkenschlager, Matthias
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768863/
https://www.ncbi.nlm.nih.gov/pubmed/19841090
http://dx.doi.org/10.1084/jem.20090226