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Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis

Blood coagulation starts immediately after damage to the vascular endothelium. This system is essential for minimizing blood loss from an injured blood vessel but also contributes to vascular thrombosis. Although it has long been thought that the intrinsic coagulation pathway is not important for cl...

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Detalles Bibliográficos
Autores principales: Decrem, Yves, Rath, Géraldine, Blasioli, Virginie, Cauchie, Philippe, Robert, Séverine, Beaufays, Jérôme, Frère, Jean-Marie, Feron, Olivier, Dogné, Jean-Michel, Dessy, Chantal, Vanhamme, Luc, Godfroid, Edmond
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768864/
https://www.ncbi.nlm.nih.gov/pubmed/19808248
http://dx.doi.org/10.1084/jem.20091007