Targeted KRAS Mutation Assessment on Patient Tumor Histologic Material in Real Time Diagnostics

BACKGROUND: Testing for tumor specific mutations on routine formalin-fixed paraffin-embedded (FFPE) tissues may predict response to treatment in Medical Oncology and has already entered diagnostics, with KRAS mutation assessment as a paradigm. The highly sensitive real time PCR (Q-PCR) methods devel...

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Detalles Bibliográficos
Autores principales: Kotoula, Vassiliki, Charalambous, Elpida, Biesmans, Bart, Malousi, Andigoni, Vrettou, Eleni, Fountzilas, George, Karkavelas, George
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768905/
https://www.ncbi.nlm.nih.gov/pubmed/19888477
http://dx.doi.org/10.1371/journal.pone.0007746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768905/
https://www.ncbi.nlm.nih.gov/pubmed/19888477
http://dx.doi.org/10.1371/journal.pone.0007746

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