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Many LINE1 elements contribute to the transcriptome of human somatic cells

BACKGROUND: While LINE1 (L1) retroelements comprise nearly 20% of the human genome, the majority are thought to have been rendered transcriptionally inactive, due to either mutation or epigenetic suppression. How many L1 elements 'escape' these forms of repression and contribute to the tra...

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Detalles Bibliográficos
Autores principales: Rangwala, Sanjida H, Zhang, Lili, Kazazian, Haig H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768975/
https://www.ncbi.nlm.nih.gov/pubmed/19772661
http://dx.doi.org/10.1186/gb-2009-10-9-r100