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Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

BACKGROUND: The continued rise of Clostridium difficile infections worldwide has been accompanied by the rapid emergence of a highly virulent clone designated PCR-ribotype 027. To understand more about the evolution of this virulent clone, we made a three-way genomic and phenotypic comparison of an...

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Detalles Bibliográficos
Autores principales: Stabler, Richard A, He, Miao, Dawson, Lisa, Martin, Melissa, Valiente, Esmeralda, Corton, Craig, Lawley, Trevor D, Sebaihia, Mohammed, Quail, Michael A, Rose, Graham, Gerding, Dale N, Gibert, Maryse, Popoff, Michel R, Parkhill, Julian, Dougan, Gordon, Wren, Brendan W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768977/
https://www.ncbi.nlm.nih.gov/pubmed/19781061
http://dx.doi.org/10.1186/gb-2009-10-9-r102