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Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network
We integrate 16 genomic features to construct an evidence-weighted functional-linkage network comprising 21,657 human genes. The functional-linkage network is used to prioritize candidate genes for 110 diseases, and to reliably disclose hidden associations between disease pairs having dissimilar phe...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768980/ https://www.ncbi.nlm.nih.gov/pubmed/19728866 http://dx.doi.org/10.1186/gb-2009-10-9-r91 |