Functional Analysis of Familial Asp67Glu and Thr1051Ser BRCA1 Mutations in Breast/Ovarian Carcinogenesis

Estrogen is believed to be pre-initiator in the risk of breast cancer. The BRCA1 is a tumor suppressor gene associated with breast and ovarian cancer risk. This report describes functional analysis of two BRCA1 missense mutations (Asp67Glu and Thr1051Ser) observed in the familial breast/ovarian canc...

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Detalles Bibliográficos
Autores principales: Pongsavee, Malinee, Patmasiriwat, Pimpicha, Saunders, Grady F.
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769146/
https://www.ncbi.nlm.nih.gov/pubmed/19865540
http://dx.doi.org/10.3390/ijms10094187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769146/
https://www.ncbi.nlm.nih.gov/pubmed/19865540
http://dx.doi.org/10.3390/ijms10094187

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