Cargando…

A Proline-Based Neuraminidase Inhibitor: DFT Studies on the Zwitterion Conformation, Stability and Formation

The designs of potent neuraminidase (NA) inhibitors are an efficient way to deal with the recent “2009 H1N1” influenza epidemic. In this work, density functional calculations were employed to study the conformation, stability and formation of the zwitterions of 5-[(1R,2S)-1-(acetylamino)-2-methoxy-2...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Zhi-Wei, Wu, Xiao-Min, Zhou, Li-Jun, Yang, Gang
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769147/
https://www.ncbi.nlm.nih.gov/pubmed/19865525
http://dx.doi.org/10.3390/ijms10093918