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Deterministic Effects Propagation Networks for reconstructing protein signaling networks from multiple interventions

BACKGROUND: Modern gene perturbation techniques, like RNA interference (RNAi), enable us to study effects of targeted interventions in cells efficiently. In combination with mRNA or protein expression data this allows to gain insights into the behavior of complex biological systems. RESULTS: In this...

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Detalles Bibliográficos
Autores principales: Fröhlich, Holger, Sahin, Özgür, Arlt, Dorit, Bender, Christian, Beißbarth, Tim
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770070/
https://www.ncbi.nlm.nih.gov/pubmed/19814779
http://dx.doi.org/10.1186/1471-2105-10-322