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Deterministic Effects Propagation Networks for reconstructing protein signaling networks from multiple interventions
BACKGROUND: Modern gene perturbation techniques, like RNA interference (RNAi), enable us to study effects of targeted interventions in cells efficiently. In combination with mRNA or protein expression data this allows to gain insights into the behavior of complex biological systems. RESULTS: In this...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770070/ https://www.ncbi.nlm.nih.gov/pubmed/19814779 http://dx.doi.org/10.1186/1471-2105-10-322 |