Identification and analysis of serpin-family genes by homology and synteny across the 12 sequenced Drosophilid genomes

BACKGROUND: The Drosophila melanogaster genome contains 29 serpin genes, 12 as single transcripts and 17 within 6 gene clusters. Many of these serpins have a conserved "hinge" motif characteristic of active proteinase inhibitors. However, a substantial proportion (42%) lacks this motif and...

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Detalles Bibliográficos
Autores principales: Garrett, Matthew, Fullaondo, Ane, Troxler, Laurent, Micklem, Gos, Gubb, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770083/
https://www.ncbi.nlm.nih.gov/pubmed/19849829
http://dx.doi.org/10.1186/1471-2164-10-489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770083/
https://www.ncbi.nlm.nih.gov/pubmed/19849829
http://dx.doi.org/10.1186/1471-2164-10-489

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