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Identification and analysis of serpin-family genes by homology and synteny across the 12 sequenced Drosophilid genomes
BACKGROUND: The Drosophila melanogaster genome contains 29 serpin genes, 12 as single transcripts and 17 within 6 gene clusters. Many of these serpins have a conserved "hinge" motif characteristic of active proteinase inhibitors. However, a substantial proportion (42%) lacks this motif and...
Autores principales: | Garrett, Matthew, Fullaondo, Ane, Troxler, Laurent, Micklem, Gos, Gubb, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770083/ https://www.ncbi.nlm.nih.gov/pubmed/19849829 http://dx.doi.org/10.1186/1471-2164-10-489 |
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