A Possible Role for Metallic Ions in the Carbohydrate Cluster Recognition Displayed by a Lewis Y Specific Antibody

BACKGROUND: Lewis Y (Le(y)) is a blood group-related carbohydrate that is expressed at high surface densities on the majority of epithelial carcinomas and is a promising target for antibody-based immunotherapy. A humanized Le(y)-specific antibody (hu3S193) has shown encouraging safety, pharmacokinet...

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Detalles Bibliográficos
Autores principales: Farrugia, William, Scott, Andrew M., Ramsland, Paul A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770121/
https://www.ncbi.nlm.nih.gov/pubmed/19901987
http://dx.doi.org/10.1371/journal.pone.0007777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770121/
https://www.ncbi.nlm.nih.gov/pubmed/19901987
http://dx.doi.org/10.1371/journal.pone.0007777

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