Immunisation with a Multivalent, Subunit Vaccine Reduces Patent Infection in a Natural Bovine Model of Onchocerciasis during Intense Field Exposure

Human onchocerciasis, caused by the filarial nematode Onchocerca volvulus, is controlled almost exclusively by the drug ivermectin, which prevents pathology by targeting the microfilariae. However, this reliance on a single control tool has led to interest in vaccination as a potentially complementa...

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Detalles Bibliográficos
Autores principales: Makepeace, Benjamin L., Jensen, Siv Aina, Laney, Sandra J., Nfon, Charles K., Njongmeta, Leo M., Tanya, Vincent N., Williams, Steven A., Bianco, Albert E., Trees, Alexander J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770122/
https://www.ncbi.nlm.nih.gov/pubmed/19901988
http://dx.doi.org/10.1371/journal.pntd.0000544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770122/
https://www.ncbi.nlm.nih.gov/pubmed/19901988
http://dx.doi.org/10.1371/journal.pntd.0000544

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