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The response of the tandem pore potassium channel TASK-3 (K(2P)9.1) to voltage: gating at the cytoplasmic mouth

Although the tandem pore potassium channel TASK-3 is thought to open and shut at its selectivity filter in response to changes of extracellular pH, it is currently unknown whether the channel also shows gating at its inner, cytoplasmic mouth through movements of membrane helices M2 and M4. We used t...

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Detalles Bibliográficos
Autores principales: Ashmole, I, Vavoulis, D V, Stansfeld, P J, Mehta, Puja R, Feng, J F, Sutcliffe, M J, Stanfield, P R
Formato: Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770146/
https://www.ncbi.nlm.nih.gov/pubmed/19703964
http://dx.doi.org/10.1113/jphysiol.2009.175430