Caenorhabditis elegans HIM-18/SLX-4 Interacts with SLX-1 and XPF-1 and Maintains Genomic Integrity in the Germline by Processing Recombination Intermediates

Homologous recombination (HR) is essential for the repair of blocked or collapsed replication forks and for the production of crossovers between homologs that promote accurate meiotic chromosome segregation. Here, we identify HIM-18, an ortholog of MUS312/Slx4, as a critical player required in vivo...

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Detalles Bibliográficos
Autores principales: Saito, Takamune T., Youds, Jillian L., Boulton, Simon J., Colaiácovo, Monica P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770170/
https://www.ncbi.nlm.nih.gov/pubmed/19936019
http://dx.doi.org/10.1371/journal.pgen.1000735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770170/
https://www.ncbi.nlm.nih.gov/pubmed/19936019
http://dx.doi.org/10.1371/journal.pgen.1000735

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