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Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways

Mammalian sterile 20-like kinase-3b (Mst3b/Stk24) regulates axon outgrowth in embryonic cortical neurons in culture, but its role in vivo and in neural repair is unknown. Here we show that Mst3b mediates the axon-promoting effects of trophic factors in mature rat retinal ganglion cells (RGCs) and do...

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Detalles Bibliográficos
Autores principales: Lorber, B., Howe, M. L., Benowitz, L. I., Irwin, N.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770175/
https://www.ncbi.nlm.nih.gov/pubmed/19855390
http://dx.doi.org/10.1038/nn.2414