Cargando…

Cell-autonomous requirement for DNaseII in non-apoptotic cell death

DNA fragmentation is a critical component of apoptosis but it has not been characterized in non-apoptotic forms of cell death, such as necrosis and autophagic cell death. In mammalian apoptosis, caspase activated DNase (CAD) cleaves DNA into nucleosomal fragments in dying cells, and subsequently DNa...

Descripción completa

Detalles Bibliográficos
Autores principales: Bass, B. Paige, Tanner, Elizabeth A., Martín, Daniel Mateos San, Blute, Todd, Kinser, Ronald D., Dolph, Patrick J., McCall, Kimberly
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770252/
https://www.ncbi.nlm.nih.gov/pubmed/19557011
http://dx.doi.org/10.1038/cdd.2009.79