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Gemcitabine and Arabinosylcytosin Pharmacogenomics: Genome-Wide Association and Drug Response Biomarkers

Cancer patients show large individual variation in their response to chemotherapeutic agents. Gemcitabine (dFdC) and AraC, two cytidine analogues, have shown significant activity against a variety of tumors. We previously used expression data from a lymphoblastoid cell line-based model system to ide...

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Detalles Bibliográficos
Autores principales: Li, Liang, Fridley, Brooke L., Kalari, Krishna, Jenkins, Gregory, Batzler, Anthony, Weinshilboum, Richard M., Wang, Liewei
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770319/
https://www.ncbi.nlm.nih.gov/pubmed/19898621
http://dx.doi.org/10.1371/journal.pone.0007765