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Phospholipase C-β4 Is Essential for the Progression of the Normal Sleep Sequence and Ultradian Body Temperature Rhythms in Mice

BACKGROUND: The sleep sequence: i) non-REM sleep, ii) REM sleep, and iii) wakefulness, is stable and widely preserved in mammals, but the underlying mechanisms are unknown. It has been shown that this sequence is disrupted by sudden REM sleep onset during active wakefulness (i.e., narcolepsy) in ore...

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Detalles Bibliográficos
Autores principales: Ikeda, Masayuki, Hirono, Moritoshi, Sugiyama, Takashi, Moriya, Takahiro, Ikeda-Sagara, Masami, Eguchi, Naomi, Urade, Yoshihiro, Yoshioka, Tohru
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770323/
https://www.ncbi.nlm.nih.gov/pubmed/19898623
http://dx.doi.org/10.1371/journal.pone.0007737