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Karyopherin binding interactions and nuclear import mechanism of nuclear pore complex protein Tpr
BACKGROUND: Tpr is a large protein with an extended coiled-coil domain that is localized within the nuclear basket of the nuclear pore complex. Previous studies [1] involving antibody microinjection into mammalian cells suggested a role for Tpr in nuclear export of proteins via the CRM1 export recep...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770460/ https://www.ncbi.nlm.nih.gov/pubmed/19835572 http://dx.doi.org/10.1186/1471-2121-10-74 |