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Karyopherin binding interactions and nuclear import mechanism of nuclear pore complex protein Tpr

BACKGROUND: Tpr is a large protein with an extended coiled-coil domain that is localized within the nuclear basket of the nuclear pore complex. Previous studies [1] involving antibody microinjection into mammalian cells suggested a role for Tpr in nuclear export of proteins via the CRM1 export recep...

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Detalles Bibliográficos
Autores principales: Ben-Efraim, Iris, Frosst, Phyllis D, Gerace, Larry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770460/
https://www.ncbi.nlm.nih.gov/pubmed/19835572
http://dx.doi.org/10.1186/1471-2121-10-74