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Karyopherin binding interactions and nuclear import mechanism of nuclear pore complex protein Tpr

BACKGROUND: Tpr is a large protein with an extended coiled-coil domain that is localized within the nuclear basket of the nuclear pore complex. Previous studies [1] involving antibody microinjection into mammalian cells suggested a role for Tpr in nuclear export of proteins via the CRM1 export recep...

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Detalles Bibliográficos
Autores principales:	Ben-Efraim, Iris, Frosst, Phyllis D, Gerace, Larry
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770460/ https://www.ncbi.nlm.nih.gov/pubmed/19835572 http://dx.doi.org/10.1186/1471-2121-10-74

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