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Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells

BACKGROUND: β-catenin mutations that constitutively activate the canonical Wnt signaling have been observed in a subset of hepatocellular carcinomas (HCCs). These mutations are associated with chromosomal stability, low histological grade, low tumor invasion and better patient survival. We hypothesi...

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Detalles Bibliográficos
Autores principales: Yuzugullu, Haluk, Benhaj, Khemais, Ozturk, Nuri, Senturk, Serif, Celik, Emine, Toylu, Asli, Tasdemir, Nilgun, Yilmaz, Mustafa, Erdal, Esra, Akcali, Kamil Can, Atabey, Nese, Ozturk, Mehmet
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770486/
https://www.ncbi.nlm.nih.gov/pubmed/19849855
http://dx.doi.org/10.1186/1476-4598-8-90