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CD74 interacts with APP and suppresses the production of Aβ
BACKGROUND: Alzheimer disease (AD) is characterized by senile plaques, which are mainly composed of β amyloid (Aβ) peptides. Aβ is cleaved off from amyloid precursor protein (APP) with consecutive proteolytic processing by β-secretase and γ-secretase. RESULTS: Here, we show that CD74, the invariant...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770512/ https://www.ncbi.nlm.nih.gov/pubmed/19849849 http://dx.doi.org/10.1186/1750-1326-4-41 |