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Human APOBEC1 cytidine deaminase edits HBV DNA

Retroviruses, hepadnaviruses, and some other retroelements are vulnerable to editing by single stranded DNA cytidine deaminases. Of the eleven human genes encoding such enzymes, eight have demonstrable enzymatic activity. Six of seven human APOBEC3 are able to hyperedit HBV DNA, frequently on both s...

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Detalles Bibliográficos
Autores principales: Gonzalez, Minerva Cervantes, Suspène, Rodolphe, Henry, Michel, Guétard, Denise, Wain-Hobson, Simon, Vartanian, Jean-Pierre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770521/
https://www.ncbi.nlm.nih.gov/pubmed/19843348
http://dx.doi.org/10.1186/1742-4690-6-96