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Comprehensive analysis of the pseudogenes of glycolytic enzymes in vertebrates: the anomalously high number of GAPDH pseudogenes highlights a recent burst of retrotrans-positional activity

BACKGROUND: Pseudogenes provide a record of the molecular evolution of genes. As glycolysis is such a highly conserved and fundamental metabolic pathway, the pseudogenes of glycolytic enzymes comprise a standardized genomic measuring stick and an ideal platform for studying molecular evolution. One...

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Detalles Bibliográficos
Autores principales: Liu, Yuen-Jong, Zheng, Deyou, Balasubramanian, Suganthi, Carriero, Nicholas, Khurana, Ekta, Robilotto, Rebecca, Gerstein, Mark B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770531/
https://www.ncbi.nlm.nih.gov/pubmed/19835609
http://dx.doi.org/10.1186/1471-2164-10-480