The influence of P-glycoprotein expression and its inhibitors on the distribution of doxorubicin in breast tumors

BACKGROUND: Anti-cancer drugs access solid tumors via blood vessels, and must penetrate tumor tissue to reach all cancer cells. Previous studies have demonstrated steep gradients of decreasing doxorubicin fluorescence with increasing distance from blood vessels, such that many tumor cells are not ex...

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Detalles Bibliográficos
Autores principales: Patel, Krupa J, Tannock, Ian F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770566/
https://www.ncbi.nlm.nih.gov/pubmed/19807929
http://dx.doi.org/10.1186/1471-2407-9-356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770566/
https://www.ncbi.nlm.nih.gov/pubmed/19807929
http://dx.doi.org/10.1186/1471-2407-9-356

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