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Novel Pandemic Influenza A(H1N1) Viruses Are Potently Inhibited by DAS181, a Sialidase Fusion Protein

BACKGROUND: The recent emergence of a novel pandemic influenza A(H1N1) strain in humans exemplifies the rapid and unpredictable nature of influenza virus evolution and the need for effective therapeutics and vaccines to control such outbreaks. However, resistance to antivirals can be a formidable pr...

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Detalles Bibliográficos
Autores principales: Triana-Baltzer, Gallen B., Gubareva, Larisa V., Nicholls, John M., Pearce, Melissa B., Mishin, Vasiliy P., Belser, Jessica A., Chen, Li-Mei, Chan, Renee W. Y., Chan, Michael C. W., Hedlund, Maria, Larson, Jeffrey L., Moss, Ronald B., Katz, Jacqueline M., Tumpey, Terrence M., Fang, Fang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770640/
https://www.ncbi.nlm.nih.gov/pubmed/19893747
http://dx.doi.org/10.1371/journal.pone.0007788