A real-time fluorescence method for enzymatic characterization of specialized human DNA polymerases

Specialized DNA polymerases are involved in DNA synthesis during base-excision repair and translesion synthesis across a wide range of chemically modified DNA templates. Notable features of these enzymes include low catalytic efficiency, low processivity and low fidelity. Traditionally, in vitro stu...

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Detalles Bibliográficos
Autores principales: Dorjsuren, Dorjbal, Wilson, David M., Beard, William A., McDonald, John P., Austin, Christopher P., Woodgate, Roger, Wilson, Samuel H., Simeonov, Anton
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770649/
https://www.ncbi.nlm.nih.gov/pubmed/19684079
http://dx.doi.org/10.1093/nar/gkp641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770649/
https://www.ncbi.nlm.nih.gov/pubmed/19684079
http://dx.doi.org/10.1093/nar/gkp641

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