RNA polymerase III can drive polycistronic expression of functional interfering RNAs designed to resemble microRNAs

In both research and therapeutic applications of RNA interference, it is often advantageous to silence several targets simultaneously. Toward this end, several groups have developed vectors that utilize the model of endogenously encoded micro (mi) RNAs, where a single RNA polymerase II promoter can...

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Detalles Bibliográficos
Autores principales: Snyder, Lindsey L., Ahmed, Iqbal, Steel, Laura F.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770651/
https://www.ncbi.nlm.nih.gov/pubmed/19679642
http://dx.doi.org/10.1093/nar/gkp657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770651/
https://www.ncbi.nlm.nih.gov/pubmed/19679642
http://dx.doi.org/10.1093/nar/gkp657

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