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Zip Nucleic Acids: new high affinity oligonucleotides as potent primers for PCR and reverse transcription
Most nucleic acid-based technologies rely upon sequence recognition between an oligonucleotide and its nucleic acid target. With the aim of improving hybridization by decreasing electrostatic repulsions between the negatively charged strands, novel modified oligonucleotides named Zip nucleic acids (...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770653/ https://www.ncbi.nlm.nih.gov/pubmed/19696078 http://dx.doi.org/10.1093/nar/gkp661 |